InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FTH1

Summary

InnateDB Protein

IDBP-812639.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FTH1

Protein Name

ferritin, heavy polypeptide 1

Synonyms

FHC; FTH; FTHL6; HFE5; PIG15; PLIF;

Species

Homo sapiens

Ensembl Protein

ENSP00000484477

InnateDB Gene

IDBG-50740 (FTH1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	54 [view]
Protein-Protein	54 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004322	ferroxidase activity
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0008199	ferric iron binding

Biological Process

GO:0006826	iron ion transport
GO:0006879	cellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion
GO:0006892	post-Golgi vesicle-mediated transport
GO:0006955	immune response
GO:0008285	negative regulation of cell proliferation
GO:0048147	negative regulation of fibroblast proliferation
GO:0055085	transmembrane transport
GO:0055114	oxidation-reduction process
GO:0061024	membrane organization