Version 5.4
Homo sapiens Protein: TPP1
Summary
InnateDB Protein IDBP-813037.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPP1
Protein Name tripeptidyl peptidase I
Synonyms CLN2; LPIC; SCAR7; TPP-1;
Species Homo sapiens
Ensembl Protein ENSP00000484546
InnateDB Gene IDBG-29461 (TPP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000209 Peptidase S8/S53 domain
IPR009020 Proteinase inhibitor, propeptide
IPR015366 Peptidase S53, propeptide
PFAM PF00082
PF09286
PRINTS
PIRSF
SMART SM00944
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PME9
UniProt Splice Variant
Entrez Gene 1200
UniGene
RefSeq
HUGO HGNC:2073
OMIM 607998
CCDS
HPRD
IMGT
EMBL AC091564
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca