Version 5.4
Homo sapiens Protein: PIK3R2
Summary
InnateDB Protein IDBP-813425.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIK3R2
Protein Name phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000484714
InnateDB Gene IDBG-37719 (PIK3R2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 122 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 122 [view]
Protein-Protein 122 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035014 phosphatidylinositol 3-kinase regulator activity
Biological Process
GO:0007165 signal transduction
GO:0043551 regulation of phosphatidylinositol 3-kinase activity
Cellular Component
GO:0005622 intracellular
GO:0005942 phosphatidylinositol 3-kinase complex
Protein Structure and Domains
PDB ID
InterPro IPR000198 Rho GTPase-activating protein domain
IPR000980 SH2 domain
IPR001452 SH3 domain
IPR001720 PI3 kinase, P85 regulatory subunit
IPR008936 Rho GTPase activation protein
PFAM PF00620
PF00017
PF14633
PF00018
PF14604
PRINTS PR00401
PR00452
PR00678
PIRSF
SMART SM00324
SM00252
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PFP1
UniProt Splice Variant
Entrez Gene 5296
UniGene
RefSeq
HUGO HGNC:8980
OMIM 603157
CCDS
HPRD
IMGT
EMBL AC007192
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca