Version 5.4
Homo sapiens Protein: STAMBPL1
Summary
InnateDB Protein IDBP-81578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAMBPL1
Protein Name STAM binding protein-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360994
InnateDB Gene IDBG-81574 (STAMBPL1)
Protein Structure
UniProt Annotation
Function Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. {ECO:0000269PubMed:18758443}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:12810066}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000555 JAB1/MPN/MOV34 metalloenzyme domain
PFAM PF01398
PRINTS
PIRSF
SMART SM00232
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96FJ0
PhosphoSite PhosphoSite-Q96FJ0
TrEMBL B3KR00
UniProt Splice Variant
Entrez Gene 57559
UniGene Hs.607504
RefSeq NP_065850
HUGO HGNC:24105
OMIM 612352
CCDS CCDS7391
HPRD 16486
IMGT
EMBL AB010120 AB037794 AK056086 AK090678 AL157394 BC010846 CH471066
GenPept AAH10846 BAA92611 BAC77766 BAG51619 BAG52212 CAI13861 CAI13862 CAI13863 EAW50156

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca