Version 5.4
Homo sapiens Protein: HECTD2
Summary
InnateDB Protein IDBP-82281.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HECTD2
Protein Name HECT domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360731
InnateDB Gene IDBG-82273 (HECTD2)
Protein Structure
UniProt Annotation
Function Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000569 HECT
PFAM PF00632
PRINTS
PIRSF
SMART SM00119
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q5U5R9
TrEMBL X6R824
UniProt Splice Variant
Entrez Gene 143279
UniGene Hs.719431
RefSeq
HUGO HGNC:26736
OMIM
CCDS
HPRD 13643
IMGT
EMBL AC023902 AK122629 AL161798
GenPept BAG53630

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca