Version 5.4
Homo sapiens Protein: WDR44
Summary
InnateDB Protein IDBP-83186.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR44
Protein Name WD repeat domain 44
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000254029
InnateDB Gene IDBG-83182 (WDR44)
Protein Structure
UniProt Annotation
Function Downstream effector for RAB11. May be involved in vesicle recycling (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Note=Colocalized with RAB11 along microtubules oriented toward lamellipodia. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5JSH3
PhosphoSite PhosphoSite-Q5JSH3
TrEMBL B7Z947
UniProt Splice Variant
Entrez Gene 54521
UniGene Hs.98510
RefSeq NP_061918
HUGO HGNC:30512
OMIM
CCDS CCDS14572
HPRD 11682
IMGT
EMBL AK001978 AK092077 AK127556 AK299711 AK304432 AL391474 AL391803 AL391830 AM393332 AM393787 BC028697 BX537578 BX538087 CH471161
GenPept AAH28697 BAA92015 BAC03799 BAC87033 BAG61611 BAH14183 CAD97788 CAD98010 CAI41402 CAI41403 CAI41482 CAI41483 CAI41512 CAI41513 CAL38210 CAL38662 EAW89896

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca