Version 5.4
Homo sapiens Protein: SYCP2
Summary
InnateDB Protein IDBP-83507.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYCP2
Protein Name synaptonemal complex protein 2
Synonyms SCP2;
Species Homo sapiens
Ensembl Protein ENSP00000360040
InnateDB Gene IDBG-83505 (SYCP2)
Protein Structure
UniProt Annotation
Function Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In axial/lateral elements of the tripartite segments of synaptonemal complexes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0007128 meiotic prophase I
GO:0007130 synaptonemal complex assembly
Cellular Component
GO:0000795 synaptonemal complex
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BX26
PhosphoSite PhosphoSite-Q9BX26
TrEMBL A2A341
UniProt Splice Variant
Entrez Gene 10388
UniGene Hs.605161
RefSeq NP_055073
HUGO HGNC:11490
OMIM 604105
CCDS CCDS13482
HPRD 06822
IMGT
EMBL AL080226 AL109928 AL158092 BC132864 BC132870 Y08982
GenPept AAI32865 AAI32871 CAA70171 CAB45780 CAC36022 CAI21795

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca