InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLPS

Summary

InnateDB Protein

IDBP-84393.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLPS

Protein Name

colipase, pancreatic

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000259938

InnateDB Gene

IDBG-84391 (CLPS)

Protein Structure

UniProt Annotation

Function

Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.Enterostatin has a biological activity as a satiety signal.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Expressed by the pancreas.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008047	enzyme activator activity

Biological Process

GO:0001523	retinoid metabolic process
GO:0006629	lipid metabolic process
GO:0007586	digestion
GO:0007603	phototransduction, visible light
GO:0016042	lipid catabolic process
GO:0043085	positive regulation of catalytic activity
GO:0044241	lipid digestion
GO:0044281	small molecule metabolic process