Version 5.4
Homo sapiens Protein: GPR21
Summary
InnateDB Protein IDBP-84478.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR21
Protein Name G protein-coupled receptor 21
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362746
InnateDB Gene IDBG-84476 (GPR21)
Protein Structure
UniProt Annotation
Function Orphan receptor.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus, hippocampus.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0040018 positive regulation of multicellular organism growth
GO:0042593 glucose homeostasis
GO:0046627 negative regulation of insulin receptor signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99679
PhosphoSite PhosphoSite-Q99679
TrEMBL H9NIL4
UniProt Splice Variant
Entrez Gene 2844
UniGene Hs.731933
RefSeq XP_005251990
HUGO HGNC:4476
OMIM 601909
CCDS CCDS6849
HPRD 03551
IMGT
EMBL AK313539 BC066885 BC066886 BC067532 BC067533 CH471090 JQ308169 U66580
GenPept AAC51303 AAH66885 AAH66886 AAH67532 AAH67533 AFF59479 BAG36316 EAW87559

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca