Version 5.4
Homo sapiens Protein: RABEPK
Summary
InnateDB Protein IDBP-85104.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RABEPK
Protein Name Rab9 effector protein with kelch motifs
Synonyms bA65N13.1; p40; RAB9P40;
Species Homo sapiens
Ensembl Protein ENSP00000259460
InnateDB Gene IDBG-85096 (RABEPK)
Protein Structure
UniProt Annotation
Function Rab9 effector required for endosome to trans-Golgi network (TGN) transport. {ECO:0000269PubMed:9230071}.
Subcellular Localization Cytoplasm. Endosome membrane. Note=Interaction with PIP5K3 and subsequent phosphorylation recruits it to the endosomal membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006904 vesicle docking involved in exocytosis
Cellular Component
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR006652 Kelch repeat type 1
IPR011498 Kelch repeat type 2
PFAM PF01344
PF07646
PRINTS
PIRSF
SMART SM00612
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z6M1
PhosphoSite PhosphoSite-Q7Z6M1
TrEMBL
UniProt Splice Variant
Entrez Gene 10244
UniGene Hs.19012
RefSeq NP_001167624
HUGO HGNC:16896
OMIM 605962
CCDS CCDS55341
HPRD 09337
IMGT
EMBL AK290768 AL354710 AL445930 AL832249 BC000503 BC047023 BC053541 BC065725 CH471090 CR456837 CR541851 Z97074
GenPept AAH00503 AAH47023 AAH53541 AAH65725 BAF83457 CAB09808 CAG33118 CAG46649 CAH10393 CAI13681 CAQ08743 EAW87616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca