InnateDB Protein
|
IDBP-85287.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
AURKAIP1
|
Protein Name
|
aurora kinase A interacting protein 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000368130
|
InnateDB Gene
|
IDBG-85279 (AURKAIP1)
|
Protein Structure
|
|
Function |
May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
|
Subcellular Localization |
Mitochondrion {ECO:0000269PubMed:23908630}. Nucleus {ECO:0000269PubMed:23908630}.
|
Disease Associations |
|
Tissue Specificity |
Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
5
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
1
[view]
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR013177
Domain of unknown function DUF1713, mitochondria
|
PFAM |
PF08213
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9NWT8
|
PhosphoSite |
PhosphoSite-Q9NWT8
|
TrEMBL |
A0A024R0F0
|
UniProt Splice Variant |
|
Entrez Gene |
54998
|
UniGene |
|
RefSeq |
NP_001120701
|
HUGO |
HGNC:24114
|
OMIM |
609183
|
CCDS |
CCDS25
|
HPRD |
16457
|
IMGT |
|
EMBL |
AK000615
AL139287
BC022808
BC062333
CH471183
|
GenPept |
AAH22808
AAH62333
BAA91289
CAI23191
EAW56218
EAW56219
|
|
|