Version 5.4
Homo sapiens Protein: CUTC
Summary
InnateDB Protein IDBP-86115.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CUTC
Protein Name cutC copper transporter homolog (E. coli)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359507
InnateDB Gene IDBG-86113 (CUTC)
Protein Structure
UniProt Annotation
Function May play a role in copper homeostasis. Can bind one Cu(1+) per subunit. {ECO:0000269PubMed:16182249, ECO:0000269PubMed:19878721}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16182249}. Nucleus {ECO:0000269PubMed:16182249}. Note=The overexpressed protein is detected in the cytoplasm, and depending on the cell line, also in the nucleus.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:16182249}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
Biological Process
GO:0006825 copper ion transport
GO:0051262 protein tetramerization
GO:0055070 copper ion homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR005627 Copper homeostasis protein CutC
IPR023648 Copper homeostasis CutC domain
PFAM PF03932
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NTM9
PhosphoSite PhosphoSite-Q9NTM9
TrEMBL Q5TCZ7
UniProt Splice Variant
Entrez Gene 51076
UniGene Hs.629067
RefSeq NP_057044
HUGO HGNC:24271
OMIM 610101
CCDS CCDS7483
HPRD 13100
IMGT
EMBL AF132966 AK314687 AL133353 BC021105 BC028948 CH471066
GenPept AAD27741 AAH21105 AAH28948 BAG37239 CAB88199 EAW49854

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca