Version 5.4
Homo sapiens Protein: SEMA4G
Summary
InnateDB Protein IDBP-86737.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA4G
Protein Name sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359270
InnateDB Gene IDBG-86729 (SEMA4G)
Protein Structure
UniProt Annotation
Function Cell surface receptor for PLXNB2. May play a role in axon guidance (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030154 cell differentiation
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001627 Sema domain
IPR002165 Plexin
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR016201 Plexin-like fold
PFAM PF01403
PF01437
PRINTS
PIRSF
SMART SM00630
SM00409
SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NTN9
PhosphoSite PhosphoSite-Q9NTN9
TrEMBL E5RGX4
UniProt Splice Variant
Entrez Gene 57715
UniGene Hs.735152
RefSeq
HUGO HGNC:10735
OMIM
CCDS
HPRD 10218
IMGT
EMBL AB046839 AL133215 BC051030 BC128579
GenPept AAH51030 AAI28580 BAB13445

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca