InnateDB Protein
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IDBP-86740.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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STMN3
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Protein Name
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stathmin-like 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000359070
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InnateDB Gene
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IDBG-86738 (STMN3)
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Protein Structure
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Function |
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. {ECO:0000250}.
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Subcellular Localization |
Golgi apparatus {ECO:0000269PubMed:21471001}. Cell projection, growth cone {ECO:0000269PubMed:21471001}. Cell projection, axon {ECO:0000269PubMed:21471001}.
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Disease Associations |
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Tissue Specificity |
Neuron specific.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
GO:0007399
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nervous system development
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GO:0031110
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regulation of microtubule polymerization or depolymerization
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GO:0031122
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cytoplasmic microtubule organization
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GO:0031175
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neuron projection development
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GO:0032314
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regulation of Rac GTPase activity
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GO:0035021
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negative regulation of Rac protein signal transduction
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GO:0051493
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regulation of cytoskeleton organization
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Cellular Component |
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PDB ID |
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InterPro |
IPR000956
Stathmin family
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PFAM |
PF00836
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PRINTS |
PR00345
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PIRSF |
PIRSF002285
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NZ72
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PhosphoSite |
PhosphoSite-Q9NZ72
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TrEMBL |
B7Z5G4
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UniProt Splice Variant |
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Entrez Gene |
50861
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UniGene |
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RefSeq |
NP_056978
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HUGO |
HGNC:15926
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OMIM |
608362
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CCDS |
CCDS13529
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HPRD |
16324
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IMGT |
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EMBL |
AF069709
AF217796
AK094112
AK298903
AL353715
BC009381
BC025234
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GenPept |
AAD12730
AAF35245
AAH09381
AAH25234
BAG52817
BAH12900
CAC16222
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