Version 5.4
Homo sapiens Protein: NPM3
Summary
InnateDB Protein IDBP-87454.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPM3
Protein Name nucleophosmin/nucleoplasmin 3
Synonyms PORMIN; TMEM123;
Species Homo sapiens
Ensembl Protein ENSP00000359128
InnateDB Gene IDBG-87452 (NPM3)
Protein Structure
UniProt Annotation
Function May act as a chaperone.
Subcellular Localization Nucleus {ECO:0000269PubMed:11722795}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:11722795}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
GO:0009303 rRNA transcription
Cellular Component
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR024057 Nucleoplasmin core domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75607
PhosphoSite PhosphoSite-O75607
TrEMBL
UniProt Splice Variant
Entrez Gene 10360
UniGene
RefSeq NP_008924
HUGO HGNC:7931
OMIM 606456
CCDS CCDS7519
HPRD 07346
IMGT
EMBL AF079325 AF081280 AY049737 BC041067 BC054868
GenPept AAC31609 AAD51496 AAH41067 AAH54868 AAL12172

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca