InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CA6

Summary

InnateDB Protein

IDBP-88414.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CA6

Protein Name

carbonic anhydrase VI

Synonyms

CA-VI; GUSTIN;

Species

Homo sapiens

Ensembl Protein

ENSP00000366662

InnateDB Gene

IDBG-88412 (CA6)

Protein Structure

UniProt Annotation

Function

Reversible hydration of carbon dioxide. Its role in saliva is unknown.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Major constituent of saliva.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004089	carbonate dehydratase activity
GO:0008270	zinc ion binding

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006730	one-carbon metabolic process
GO:0015701	bicarbonate transport
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001148 Alpha carbonic anhydrase

PFAM

PF00194

PRINTS

PIRSF

SMART

SM01057

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P23280

PhosphoSite

PhosphoSite-

TrEMBL

B4DUH8

UniProt Splice Variant

Entrez Gene

765

UniGene

RefSeq

NP_001257431

HUGO

HGNC:1380

OMIM

114780

CCDS

CCDS30578

HPRD

00264

IMGT

EMBL

AB102863 AB103091 AF128411 AF128412 AF128413 AF128414 AF128415 AF128416 AF128417 AF128418 AK300652 AL139415 M57892

GenPept

AAA51892 AAF22565 BAD89397 BAD89434 BAG62340 CAC42429