InnateDB Protein
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IDBP-88800.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CD99L2
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Protein Name
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CD99 molecule-like 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000347275
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InnateDB Gene
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IDBG-88792 (CD99L2)
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Protein Structure
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Function |
Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Cell junction {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in many tissues, with low expression in thymus. {ECO:0000269PubMed:12706889}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR022078
CD99 antigen-like protein 2
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PFAM |
PF12301
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TCZ2
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PhosphoSite |
PhosphoSite-Q8TCZ2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
83692
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UniGene |
Hs.701870
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RefSeq |
NP_604394
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HUGO |
HGNC:18237
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OMIM |
300846
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CCDS |
CCDS14697
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HPRD |
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IMGT |
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EMBL |
AF002223
AF274573
AK125020
AK290200
AK291375
AK293244
AL136580
AY078165
AY078166
AY078167
AY358837
BC025729
BC030536
CH471169
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GenPept |
AAH25729
AAH30536
AAL86617
AAL86618
AAL86619
AAQ89196
BAF82889
BAF84064
BAG54124
BAG56778
CAB66515
EAW99391
EAW99392
EAW99393
EAW99395
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