InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP188

Summary

InnateDB Protein

IDBP-88855.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP188

Protein Name

nucleoporin 188kDa

Synonyms

hNup188; KIAA0169;

Species

Homo sapiens

Ensembl Protein

ENSP00000361658

InnateDB Gene

IDBG-88853 (NUP188)

Protein Structure

UniProt Annotation

Function

May function as a component of the nuclear pore complex (NPC).

Subcellular Localization

Nucleus, nuclear pore complex {ECO:0000305}.

Disease Associations

Note=Copy number variations of NUP188 gene may be a cause of heterotaxy, a congenital heart disease resulting from abnormalities in left-right (LR) body patterning. {ECO:0000269PubMed:21282601}.

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0055085	transmembrane transport