Version 5.4
Homo sapiens Protein: ITPRIP
Summary
InnateDB Protein IDBP-88891.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITPRIP
Protein Name inositol 1,4,5-trisphosphate receptor interacting protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000350915
InnateDB Gene IDBG-88885 (ITPRIP)
Protein Structure
UniProt Annotation
Function Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release. {ECO:0000269PubMed:16990268}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:16990268}.
Disease Associations
Tissue Specificity Detected in brain where it is concentrated in cerebellar Purkinje cells (at protein level). {ECO:0000269PubMed:16990268}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IWB1
PhosphoSite PhosphoSite-Q8IWB1
TrEMBL X6RK76
UniProt Splice Variant
Entrez Gene 85450
UniGene Hs.523252
RefSeq NP_001258941
HUGO HGNC:29370
OMIM
CCDS CCDS7557
HPRD 13892
IMGT
EMBL AB051541 AK056526 AL162742 BC040536 BC070108 CH471066
GenPept AAH40536 AAH70108 BAB21845 BAB71204 CAI12108 CAI12109 EAW49596 EAW49597

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca