Version 5.4
Homo sapiens Protein: EBF3
Summary
InnateDB Protein IDBP-93216.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EBF3
Protein Name early B-cell factor 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000347463
InnateDB Gene IDBG-93214 (EBF3)
Protein Structure
UniProt Annotation
Function Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain. {ECO:0000269PubMed:12355068}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007275 multicellular organismal development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR002909 IPT domain
IPR014756 Immunoglobulin E-set
PFAM PF01833
PRINTS
PIRSF
SMART SM00429
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H4W6
PhosphoSite PhosphoSite-Q9H4W6
TrEMBL
UniProt Splice Variant
Entrez Gene 253738
UniGene Hs.713683
RefSeq XP_005252724
HUGO HGNC:19087
OMIM 607407
CCDS
HPRD 16818
IMGT
EMBL AL354950 BC126130 BC130479 CH471066
GenPept AAI26131 AAI30480 CAI12792 CAI12793 EAW49160

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca