InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TBX18

Summary

InnateDB Protein

IDBP-93975.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TBX18

Protein Name

T-box 18

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000358677

InnateDB Gene

IDBG-93971 (TBX18)

Protein Structure

UniProt Annotation

Function

Probable transcriptional regulator involved in developmental processes.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00201}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0001106	RNA polymerase II transcription corepressor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001756	somitogenesis
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0003163	sinoatrial node development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007605	sensory perception of sound
GO:0009948	anterior/posterior axis specification
GO:0016331	morphogenesis of embryonic epithelium
GO:0022409	positive regulation of cell-cell adhesion
GO:0030154	cell differentiation
GO:0048646	anatomical structure formation involved in morphogenesis
GO:0050679	positive regulation of epithelial cell proliferation
GO:0051145	smooth muscle cell differentiation
GO:0060829	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0072189	ureter development
GO:0090103	cochlea morphogenesis
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development