InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RHCE

Summary

InnateDB Protein

IDBP-94331.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RHCE

Protein Name

Rh blood group, CcEe antigens

Synonyms

CD240CE; RH; RH30A; Rh4; RHC; RHE; RhIVb(J); RHIXB; RHPI; RhVI; RhVIII;

Species

Homo sapiens

Ensembl Protein

ENSP00000294413

InnateDB Gene

IDBG-94329 (RHCE)

Protein Structure

UniProt Annotation

Function

May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Restricted to tissues or cell lines expressing erythroid characters. Isoform 4g and isoform RhPI-Alpha are expressed in immature erythroblasts but not in mature erythroblasts. {ECO:0000269PubMed:8117271}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008519	ammonium transmembrane transporter activity

Biological Process

GO:0015696	ammonium transport
GO:0072488	ammonium transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002229 Blood group Rhesus C/E/D polypeptide
IPR024041 Ammonium transporter AmtB-like domain

PFAM

PF00909

PRINTS

PR00342

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P18577

PhosphoSite

PhosphoSite-P18577

TrEMBL

W6B6B2

UniProt Splice Variant

Entrez Gene

6006

UniGene

Hs.523054

RefSeq

NP_065231

HUGO

HGNC:10008

OMIM

111700

CCDS

CCDS30635

HPRD

00200

IMGT

EMBL

AB016502 AB018644 AB018645 AB030388 AB049753 AF056967 AF510065 AF510066 AF510067 AF510068 AJ504793 AL031284 AL928711 AM398146 AM902714 AY603478 AY756316 BC075081 BC139905 BN000065 DQ178642 DQ266353 DQ266400 DQ322275 FJ486155 FJ486156 FJ486157 FJ486158 FJ486159 FJ486160 FJ486161 FJ486162 FJ486163 FJ486164 FJ486165 FM866414 FM866415 FM866416 FM866419 FM883601 FN555130 FN555131 FN998903 FR692355 HQ665313 KF861928 M34015 S57967 S70456 X54534 X63095 X63096 X63098

GenPept

AAA36567 AAB26080 AAC18094 AAD14061 AAH75081 AAI39906 AAN75121 AAN75122 AAN75123 AAN75124 AAT35811 AAV51934 ABA25912 ABB69097 ABB97471 ABC55358 ACK75562 ACK75563 ACK75564 ACK75565 ACK75566 ACK75567 ACK75568 ACK75569 ACK75570 ACK75571 ACK75572 AEI91025 AHI62999 BAA33927 BAA33928 BAA36696 BAA82627 BAB16597 CAA38401 CAA44809 CAA44810 CAA44812 CAD29850 CAD43297 CAH72605 CAL44958 CAM12858 CAP18774 CAS02276 CAS02277 CAS02278 CAS02281 CAT05639 CBG76068 CBG76069 CBS91666 CBX23453