InnateDB Protein
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IDBP-96204.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ECHDC1
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Protein Name
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enoyl CoA hydratase domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000357272
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InnateDB Gene
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IDBG-96186 (ECHDC1)
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Protein Structure
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Function |
Decarboxylases ethylmalonyl-CoA decarboxylase, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level. {ECO:0000269PubMed:22016388}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001753
Crotonase superfamily
IPR029045
ClpP/crotonase-like domain
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PFAM |
PF00378
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NTX5
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PhosphoSite |
PhosphoSite-Q9NTX5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
55862
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UniGene |
Hs.685427
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RefSeq |
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HUGO |
HGNC:21489
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OMIM |
612136
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CCDS |
CCDS34530
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HPRD |
13260
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IMGT |
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EMBL |
AF220192
AK303812
AL109939
AL834469
BC003549
CH471051
EU668355
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GenPept |
AAF67657
AAH03549
ACF94508
BAH14056
CAB76256
CAD39128
CAI20295
CAI20297
CAI20298
CAI20302
EAW48107
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