InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PARS2

Summary

InnateDB Protein

IDBP-99043.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PARS2

Protein Name

prolyl-tRNA synthetase 2, mitochondrial (putative)

Synonyms

MT-PRORS;

Species

Homo sapiens

Ensembl Protein

ENSP00000360327

InnateDB Gene

IDBG-99041 (PARS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004827	proline-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006433	prolyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002314 Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain
IPR002316 Proline-tRNA ligase, class IIa
IPR004154 Anticodon-binding
IPR006195 Aminoacyl-tRNA synthetase, class II

PFAM

PF00587
PF03129

PRINTS

PR01046

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7L3T8