InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ELTD1

Summary

InnateDB Protein

IDBP-99884.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELTD1

Protein Name

EGF, latrophilin and seven transmembrane domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000359778

InnateDB Gene

IDBG-99882 (ELTD1)

Protein Structure

UniProt Annotation

Function

Could be involved in cardiac development.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Mainly expressed in smooth muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000203 GPS motif
IPR000742 Epidermal growth factor-like domain
IPR000832 GPCR, family 2, secretin-like
IPR001881 EGF-like calcium-binding domain
IPR017981 GPCR, family 2-like
IPR022624 Domain of unknown function DUF3497

PFAM

PF01825
PF00008
PF00002
PF07645
PF12003

PRINTS

PR00249

PIRSF

SMART

SM00303
SM00181
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt