Version 5.4
Homo sapiens Gene: SNX7
Summary
InnateDB Gene IDBG-100424.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX7
Gene Name sorting nexin 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162627
Encoded Proteins
IDBP-100426
sorting nexin 7
IDBP-387051
sorting nexin 7
IDBP-586835
sorting nexin 7
IDBP-601466
sorting nexin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:98661701-98760500
Strand Forward strand
Band p21.3
Transcripts
ENST00000306121 ENSP00000304429
ENST00000454199 ENSP00000388266
ENST00000473868
ENST00000529992 ENSP00000434731
ENST00000528824 ENSP00000435172
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006915 apoptotic process
Cellular Component
GO:0005768 endosome
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028007
View Gene Order
ENSBTAG00000031461
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.197015
RefSeq NM_015976 NM_152238
HUGO
OMIM
CCDS CCDS755 CCDS756
HPRD 15416
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca