Version 5.4
| Homo sapiens Gene: AMY1B | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-100605.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | AMY1B | ||||||||||||||||||
| Gene Name | amylase, alpha 1B (salivary) | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000174876 | ||||||||||||||||||
| Encoded Proteins |
amylase, alpha 1B (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1B (salivary)
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. [provided by RefSeq, Jul 2008] Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 1:103687415-103696680 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p21.1 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Digestion of dietary carbohydrate pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
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| KEGG |
Starch and sucrose metabolism pathway
Salivary secretion pathway
Carbohydrate digestion and absorption pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | P04745 | ||||||||||||||||||
| TrEMBL | Q5T084 Q5T085 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 278 | ||||||||||||||||||
| UniGene | Hs.599274 Hs.655232 | ||||||||||||||||||
| RefSeq | NM_001008218 | ||||||||||||||||||
| HUGO | HGNC:475 | ||||||||||||||||||
| OMIM | 104700 104701 104702 | ||||||||||||||||||
| CCDS | CCDS30783 | ||||||||||||||||||
| HPRD | 18510 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC105272 AK292341 AL513482 BC063129 BC069347 BC069463 BC092444 BC132985 BC132987 BC132995 BC132997 M17883 M17884 M18671 M18674 M18715 M18717 M18719 M18721 M18723 M18725 M18727 M18784 M18786 M19233 | ||||||||||||||||||
| GenPept | AAA16183 AAA52279 AAA57345 AAA58368 AAH63129 AAH69347 AAH69463 AAH92444 AAI32986 AAI32988 AAI32996 AAI32998 BAF85030 CAI14928 CAI14932 | ||||||||||||||||||
| RNA Seq Atlas | 276 277 278 | ||||||||||||||||||