Homo sapiens Gene: FCRLA
Summary
InnateDB Gene IDBG-104321.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRLA
Gene Name Fc receptor-like A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132185
Encoded Proteins
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Fc receptor-like A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:161706972-161714352
Strand Forward strand
Band q23.3
Transcripts
ENST00000367959 ENSP00000356936
ENST00000236938 ENSP00000236938
ENST00000309691 ENSP00000309596
ENST00000349527 ENSP00000294798
ENST00000367957 ENSP00000356934
ENST00000350710 ENSP00000344808
ENST00000367953 ENSP00000356930
ENST00000294796 ENSP00000294796
ENST00000367950 ENSP00000356927
ENST00000367949 ENSP00000356926
ENST00000465403
ENST00000470841
ENST00000546024 ENSP00000439838
ENST00000540521 ENSP00000442870
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030154 cell differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q7L513
TrEMBL A6NC03 A6NL20 F5H720 F8W743 G3V1J2 Q5VXA5 Q5VXB1 Q6MZF2
UniProt Splice Variant
Entrez Gene 84824
UniGene Hs.266331
RefSeq NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738 XM_006711581
HUGO HGNC:18504
OMIM 606891
CCDS CCDS30926 CCDS53415 CCDS53416 CCDS53417 CCDS53418 CCDS53419 CCDS53420
HPRD
IMGT
EMBL AF329489 AF329491 AF329493 AF329494 AF329495 AF390036 AF426461 AF531423 AL359541 AY091642 AY358348 BC006521 BX649184 CH471067 EF064729
GenPept AAH06521 AAL23899 AAL23901 AAL23903 AAL23904 AAL23905 AAL27307 AAL58111 AAM13980 AAM97591 AAQ88714 ABK41912 CAE46202 CAH74157 CAH74158 CAH74159 CAH74160 CAH74162 EAW90683 EAW90684 EAW90685
RNA Seq Atlas 84824