Homo sapiens Gene: GPA33
Summary
InnateDB Gene IDBG-104526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPA33
Gene Name glycoprotein A33 (transmembrane)
Synonyms A33
Species Homo sapiens
Ensembl Gene ENSG00000143167
Encoded Proteins
glycoprotein A33 (transmembrane)
glycoprotein A33 (transmembrane)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95%% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:167052836-167090631
Strand Reverse strand
Band q24.1
Transcripts
ENST00000367868 ENSP00000356842
ENST00000527955
ENST00000534512 ENSP00000431195
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q99795
TrEMBL
UniProt Splice Variant
Entrez Gene 10223
UniGene Hs.651244
RefSeq NM_005814
HUGO HGNC:4445
OMIM 602171
CCDS CCDS1258
HPRD 03704
IMGT
EMBL AK312833 AL158837 BC069705 BC069723 BC069745 BC069761 BC069789 BC074830 BC074876 BC107164 BC107165 CH471067 U79725
GenPept AAC50957 AAH69705 AAH69723 AAH69745 AAH69761 AAH69789 AAH74830 AAH74876 AAI07165 AAI07166 BAG35687 CAH69957 EAW90783
RNA Seq Atlas 10223