Version 5.4
Homo sapiens Gene: APOBEC4
Summary
InnateDB Gene IDBG-105333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOBEC4
Gene Name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173627
Encoded Proteins
IDBP-105335
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:183646404-183653316
Strand Reverse strand
Band q25.3
Transcripts
ENST00000308641 ENSP00000310622
ENST00000481562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
Biological Process
GO:0006397 mRNA processing
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055547
View Gene Order
ENSBTAG00000047395
Not yet available
Cross-References
SwissProt Q8WW27
TrEMBL
UniProt Splice Variant
Entrez Gene 403314
UniGene Hs.97335
RefSeq NM_203454
HUGO HGNC:32152
OMIM 609908
CCDS CCDS1358
HPRD
IMGT
EMBL AK098557 AL137800 BC021711
GenPept AAH21711 BAC05332 CAI19483
RNA Seq Atlas 403314

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca