Version 5.4
Homo sapiens Gene: ETNK2
Summary
InnateDB Gene IDBG-106011.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETNK2
Gene Name ethanolamine kinase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143845
Encoded Proteins
IDBP-106013
ethanolamine kinase 2
IDBP-106015
ethanolamine kinase 2
IDBP-106021
ethanolamine kinase 2
IDBP-389923
ethanolamine kinase 2
IDBP-389925
ethanolamine kinase 2
IDBP-389926
ethanolamine kinase 2
IDBP-389927
ethanolamine kinase 2
IDBP-389928
ethanolamine kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of choline/ethanolamine kinase family which catalyzes the first step of phosphatidylethanolamine (PtdEtn) biosynthesis via the cytidine diphosphate (CDP) ethanolamine pathway. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:204131062-204152003
Strand Reverse strand
Band q32.1
Transcripts
ENST00000367202 ENSP00000356170
ENST00000367201 ENSP00000356169
ENST00000367197 ENSP00000356165
ENST00000422072 ENSP00000410580
ENST00000422699 ENSP00000405497
ENST00000452983 ENSP00000398091
ENST00000444817 ENSP00000406241
ENST00000429525 ENSP00000394618
ENST00000472340
ENST00000492392
ENST00000477125
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004305 ethanolamine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001701 in utero embryonic development
GO:0001890 placenta development
GO:0006644 phospholipid metabolic process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009791 post-embryonic development
GO:0016310 phosphorylation
GO:0035264 multicellular organism growth
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070644
View Gene Order
ENSBTAG00000018509
Not yet available
Pathways
NETPATH
REACTOME
REACT_120919
Synthesis of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.497469
RefSeq NM_001297760 NM_018208 XM_005245302
HUGO
OMIM
CCDS CCDS1442 CCDS73006
HPRD 13283
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca