Homo sapiens Gene: SLC30A10
Summary
InnateDB Gene IDBG-106720.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC30A10
Gene Name solute carrier family 30, member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196660
Encoded Proteins
solute carrier family 30, member 10
solute carrier family 30, member 10
Protein Structure
Entrez Gene
Summary This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:219685427-219958647
Strand Reverse strand
Band q41
Transcripts
ENST00000356609 ENSP00000349018
ENST00000366926 ENSP00000355893
ENST00000484239
ENST00000484079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0006829 zinc ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q6XR72
TrEMBL B3KR19
UniProt Splice Variant
Entrez Gene 55532
UniGene Hs.284450
RefSeq NM_018713 XM_006711438 XM_006711439
HUGO HGNC:25355
OMIM 611146
CCDS CCDS31026
HPRD 15367
IMGT
EMBL AC093562 AK090806 AL359609 AY212919 BC036078 CH471100
GenPept AAH36078 AAP44332 BAG52231 CAB94880 EAW93312 EAW93314
ImmGen SLC30A10 (murine)
RNA Seq Atlas 55532