Homo sapiens Gene: FBXO28
Summary
InnateDB Gene IDBG-106888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO28
Gene Name F-box protein 28
Synonyms CENP-30; Fbx28
Species Homo sapiens
Ensembl Gene ENSG00000143756
Encoded Proteins
F-box protein 28
F-box protein 28
F-box protein 28
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:224114087-224162047
Strand Forward strand
Band q42.11
Transcripts
ENST00000366862 ENSP00000355827
ENST00000424254 ENSP00000416888
ENST00000523990 ENSP00000430632
ENST00000483773
ENST00000519894
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9NVF7
TrEMBL B4E0H5
UniProt Splice Variant
Entrez Gene 23219
UniGene Hs.606626 Hs.64691 Hs.713992
RefSeq NM_001136115 NM_015176
HUGO HGNC:29046
OMIM 609100
CCDS CCDS44320 CCDS1539
HPRD 12367
IMGT
EMBL AB007952 AK001628 AK303381 AL390122 BC031576
GenPept AAH31576 BAA32327 BAA91795 BAG64437 CAH70934
RNA Seq Atlas 23219