Version 5.4
Homo sapiens Gene: FMN2
Summary
InnateDB Gene IDBG-107664.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FMN2
Gene Name formin 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000155816
Encoded Proteins
IDBP-107666
formin 2
IDBP-390174
formin 2
IDBP-390176
formin 2
IDBP-587410
formin 2
IDBP-601038
formin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:240014348-240475189
Strand Forward strand
Band q43
Transcripts
ENST00000319653 ENSP00000318884
ENST00000447095 ENSP00000409308
ENST00000441342 ENSP00000388922
ENST00000463398
ENST00000496950
ENST00000545751 ENSP00000437918
ENST00000543681 ENSP00000439136
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0007275 multicellular organismal development
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0016344 meiotic chromosome movement towards spindle pole
GO:0035556 intracellular signal transduction
GO:0040038 polar body extrusion after meiotic divisions
GO:0042177 negative regulation of protein catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0045010 actin nucleation
GO:0046907 intracellular transport
GO:0048477 oogenesis
GO:0051017 actin filament bundle assembly
GO:0051295 establishment of meiotic spindle localization
GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation
GO:0070649 formin-nucleated actin cable assembly
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005575 cellular_component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005819 spindle
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005938 cell cortex
GO:0015629 actin cytoskeleton
GO:0030659 cytoplasmic vesicle membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028354
View Gene Order
ENSBTAG00000025021
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04320
Dorso-ventral axis formation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.24889
RefSeq NM_020066 XM_005273200
HUGO
OMIM
CCDS CCDS31069
HPRD 10449
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca