Homo sapiens Gene: MRPL36
Summary
InnateDB Gene IDBG-11265.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL36
Gene Name mitochondrial ribosomal protein L36
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171421
Encoded Proteins
mitochondrial ribosomal protein L36
mitochondrial ribosomal protein L36
mitochondrial ribosomal protein L36
mitochondrial ribosomal protein L36
mitochondrial ribosomal protein L36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:1798386-1801366
Strand Reverse strand
Band p15.33
Transcripts
ENST00000382647 ENSP00000372093
ENST00000505818 ENSP00000427152
ENST00000505059 ENSP00000423152
ENST00000508987 ENSP00000423399
ENST00000510999 ENSP00000424366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9P0J6
TrEMBL D6RB74
UniProt Splice Variant
Entrez Gene 64979
UniGene
RefSeq NM_032479
HUGO HGNC:14490
OMIM 611842
CCDS CCDS3865
HPRD
IMGT
EMBL AB049654 AC026443 AF151109 AF155653 AK312001 BC020642 BC104652 CH471102 EF036487
GenPept AAF04788 AAF67010 AAH20642 AAI04653 ABO65073 BAB40859 BAG34939 EAX08145
RNA Seq Atlas 64979