Version 5.4
Homo sapiens Gene: DNAL1
Summary
InnateDB Gene IDBG-11598.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAL1
Gene Name dynein, axonemal, light chain 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000119661
Encoded Proteins
IDBP-11600
dynein, axonemal, light chain 1
IDBP-596867
dynein, axonemal, light chain 1
IDBP-583683
dynein, axonemal, light chain 1
IDBP-593499
dynein, axonemal, light chain 1
IDBP-583284
dynein, axonemal, light chain 1
IDBP-594298
dynein, axonemal, light chain 1
IDBP-589300
dynein, axonemal, light chain 1
IDBP-601140
dynein, axonemal, light chain 1
IDBP-598440
dynein, axonemal, light chain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:73644875-73703732
Strand Forward strand
Band q24.3
Transcripts
ENST00000311089 ENSP00000310360
ENST00000554113 ENSP00000452368
ENST00000555631 ENSP00000451547
ENST00000553645 ENSP00000452037
ENST00000555919 ENSP00000451101
ENST00000554339 ENSP00000450744
ENST00000554871 ENSP00000451834
ENST00000559993 ENSP00000453439
ENST00000554159 ENSP00000451264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042523
View Gene Order
ENSBTAG00000015930
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.271270
RefSeq NM_001201366 NM_031427
HUGO
OMIM
CCDS CCDS45134 CCDS55928
HPRD 16616
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca