Version 5.4
Homo sapiens Gene: OR2C1
Summary
InnateDB Gene IDBG-11879.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR2C1
Gene Name olfactory receptor, family 2, subfamily C, member 1
Synonyms OLFmf3; OR2C2P
Species Homo sapiens
Ensembl Gene ENSG00000168158
Encoded Proteins
IDBP-11881
olfactory receptor, family 2, subfamily C, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:3355889-3357294
Strand Forward strand
Band p13.3
Transcripts
ENST00000304936 ENSP00000307726
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059043
View Gene Order
ENSBTAG00000001606
Not yet available
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt O95371
TrEMBL
UniProt Splice Variant
Entrez Gene 4993
UniGene
RefSeq NM_012368 XM_006720887 XM_006720888
HUGO HGNC:8242
OMIM
CCDS CCDS10502
HPRD
IMGT
EMBL AC025283 AF098664 BC069456 BC126269 BC130328 BK004407 BK004428 CH471112
GenPept AAC83557 AAH69456 AAI26270 AAI30329 DAA04805 DAA04826 EAW85373
RNA Seq Atlas 4993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca