Homo sapiens Gene: FBXO46
Summary
InnateDB Gene IDBG-120694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO46
Gene Name F-box protein 46
Synonyms 20D7-FC4; Fbx46; FBXO34L
Species Homo sapiens
Ensembl Gene ENSG00000177051
Encoded Proteins
F-box protein 46
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:45710629-45730904
Strand Reverse strand
Band q13.32
Transcripts
ENST00000317683 ENSP00000410007
ENST00000586899 ENSP00000468336
ENST00000591686 ENSP00000465591
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.128702 Hs.570021
RefSeq NM_001080469
HUGO
OMIM
CCDS CCDS46116
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas