Homo sapiens Gene: RMRP

Summary
InnateDB Gene IDBG-121897.4
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol RMRP
Gene Name RNA component of mitochondrial RNA processing endoribonuclease
Synonyms CHH; NME1; RMRPR; RRP2
Species Homo sapiens
Ensembl Gene ENSG00000199916
Encoded Proteins
Entrez Gene
Summary This gene encodes the RNA component of mitochondrial RNA processing endoribonuclease, which cleaves mitochondrial RNA at a priming site of mitochondrial DNA replication. This RNA also interacts with the telomerase reverse transcriptase catalytic subunit to form a distinct ribonucleoprotein complex that has RNA-dependent RNA polymerase activity and produces double-stranded RNAs that can be processed into small interfering RNA. Mutations in this gene are associated with cartilage-hair hypoplasia.[provided by RefSeq, Mar 2010]
Gene Information
Type misc_RNA
Genomic Location Chromosome 9: 35657751-35658014
Strand Reverse strand
Band p13.3
Transcripts
ENST00000363046 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein‑Protein  1
[view]
Protein‑DNA 0
Protein‑RNA 1
[view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
Biological Process
Cellular Component
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 6023 
UniGene Hs.587502
RefSeq
HUGO 10031 
OMIM 157660
CCDS
HPRD
IMGT
EMBL
GenPept
ImmGen RMRP (murine) 
RNA Seq Atlas 6023