Version 5.4
Homo sapiens Gene: LTN1
Summary
InnateDB Gene IDBG-1246.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LTN1
Gene Name listerin E3 ubiquitin protein ligase 1
Synonyms C21orf10; C21orf98; RNF160; ZNF294
Species Homo sapiens
Ensembl Gene ENSG00000198862
Encoded Proteins
IDBP-1248
listerin E3 ubiquitin protein ligase 1
IDBP-1250
listerin E3 ubiquitin protein ligase 1
IDBP-1252
listerin E3 ubiquitin protein ligase 1
IDBP-809941
listerin E3 ubiquitin protein ligase 1
IDBP-809942
listerin E3 ubiquitin protein ligase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:28928144-28992956
Strand Reverse strand
Band q21.3
Transcripts
ENST00000361371 ENSP00000354977
ENST00000389195 ENSP00000373847
ENST00000389194 ENSP00000373846
ENST00000486427
ENST00000475344
ENST00000483326 ENSP00000474690
ENST00000614971 ENSP00000478783
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0051865 protein autoubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000052299
View Gene Order
ENSBTAG00000000201
Not yet available
Cross-References
SwissProt O94822
TrEMBL G1UI34
UniProt Splice Variant
Entrez Gene 26046
UniGene Hs.288773 Hs.596047
RefSeq NM_015565 XM_006723987
HUGO HGNC:13082
OMIM 613083
CCDS CCDS33527
HPRD 10327
IMGT
EMBL AB018257 AB621822 AF129075 AF161350 AF260011 AK001915 AK023499 AL163248 AL163249 BC029371 BC140790 BC150284 DB452437
GenPept AAF28910 AAH29371 AAI40791 AAI50285 BAA34434 BAA91976 BAB14589 BAK64157 CAB90429 CAB90430
RNA Seq Atlas 26046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca