Version 5.4
Mus musculus Gene: Sepp1
Summary
InnateDB Gene IDBG-127862.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sepp1
Gene Name selenoprotein P, plasma, 1
Synonyms AU018766; D15Ucla1; Se-P; selp
Species Mus musculus
Ensembl Gene ENSMUSG00000064373
Encoded Proteins
IDBP-127864
selenoprotein P, plasma, 1
IDBP-533506
selenoprotein P, plasma, 1
IDBP-533923
selenoprotein P, plasma, 1
IDBP-541806
selenoprotein P, plasma, 1
IDBP-542287
selenoprotein P, plasma, 1
IDBP-540038
selenoprotein P, plasma, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is a secreted protein, and is unusual in that it contains 10 selenocysteine residues per polypeptide, constituting most of the selenium in plasma. It has been implicated as an extracellular antioxidant and in the transport of selenium. Several transcript variants differing in the 5\' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:3268547-3280508
Strand Forward strand
Band A1
Transcripts
ENSMUST00000082424 ENSMUSP00000081004
ENSMUST00000160787 ENSMUSP00000124852
ENSMUST00000159158 ENSMUSP00000125632
ENSMUST00000159216 ENSMUSP00000124305
ENSMUST00000160311 ENSMUSP00000124580
ENSMUST00000159247
ENSMUST00000160930 ENSMUSP00000125505
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008430 selenium binding
Biological Process
GO:0001887 selenium compound metabolic process
GO:0007420 brain development
GO:0007626 locomotory behavior
GO:0009791 post-embryonic development
GO:0019953 sexual reproduction
GO:0040007 growth
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000250722
View Gene Order
Cross-References
SwissProt P70274
TrEMBL
UniProt Splice Variant
Entrez Gene 20363
UniGene Mm.392203 Mm.471741
RefSeq NM_001042614 NM_009155 NM_001042613
OMIM
CCDS CCDS27357
HPRD
IMGT
MGI ID MGI:894288
MGI Symbol Sepp1
EMBL AF021345 AK002450 AK077265 AK146774 AK148623 AK159269 AK159524 AK159894 AK159911 AK159935 AK167611 AK168463 AK168583 AK168631 AK168747 AK168926 AK169011 AK169158 AK169362 BC001991 X99807
GenPept AAD01684 AAH01991 BAC55246 BAC55264 BAE27423 BAE28626 BAE34948 BAE35153 BAE35460 BAE35474 BAE35495 BAE39664 BAE40359 BAE40452 BAE40491 BAE40587 BAE40739 BAE40808 BAE40937 BAE41111 CAA68140
RNA Seq Atlas 20363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca