Mus musculus Gene: C6 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-127938.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | C6 | ||||||||||
Gene Name | complement component 6 | ||||||||||
Synonyms | AW111623 | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Gene | ENSMUSG00000022181 | ||||||||||
Encoded Proteins |
complement component 6
complement component 6
complement component 6
complement component 6
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
InnateDB Annotation from Orthologs | |||||||||||
Summary |
[Homo sapiens] Complement component six is one of five components that interact to form the cytolytic membrane attack complex (MAC)
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Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000039537:
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 15:4727175-4815456 | ||||||||||
Strand | Forward strand | ||||||||||
Band | A1 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG |
Complement and coagulation cascades pathway
Systemic lupus erythematosus pathway
Prion diseases pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME |
Terminal pathway of complement pathway
Regulation of Complement cascade pathway
Innate Immune System pathway
Immune System pathway
Complement cascade pathway
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KEGG |
Complement and coagulation cascades pathway
Systemic lupus erythematosus pathway
Prion diseases pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Mm.20247 | ||||||||||
RefSeq | NM_016704 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS37025 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
MGI ID | |||||||||||
MGI Symbol | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||