Version 5.4
Mus musculus Gene: Gen1
Summary
InnateDB Gene IDBG-128736.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gen1
Gene Name Gen homolog 1, endonuclease (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000051235
Encoded Proteins
IDBP-623138
Gen homolog 1, endonuclease (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178295:
Gene Information
Type Protein coding
Genomic Location Chromosome 12:11240926-11265787
Strand Reverse strand
Band A1.1
Transcripts
ENSMUST00000166117 ENSMUSP00000132098
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0008821 crossover junction endodeoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000737 DNA catabolic process, endonucleolytic
GO:0006281 DNA repair
GO:0010824 regulation of centrosome duplication
GO:0071139 resolution of recombination intermediates
GO:0071140 resolution of mitotic recombination intermediates
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000178295
View Gene Order
ENSBTAG00000020059
Not yet available
Cross-References
SwissProt Q8BMI4
TrEMBL
UniProt Splice Variant
Entrez Gene 209334
UniGene Mm.215295
RefSeq NM_177331 XM_006515039 XM_006515040 XM_006515041
OMIM
CCDS CCDS36403
HPRD
IMGT
MGI ID MGI:2443149
MGI Symbol Gen1
EMBL AK030995 AK031077 AK158255 BC090653 BC138157 BC138158
GenPept AAH90653 AAI38158 AAI38159 BAC27207 BAC27242 BAE34428
RNA Seq Atlas 209334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca