Version 5.4
Mus musculus Gene: Tbc1d10c
Summary
InnateDB Gene IDBG-129155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d10c
Gene Name TBC1 domain family, member 10c
Synonyms 1810062O14Rik; AI428527
Species Mus musculus
Ensembl Gene ENSMUSG00000040247
Encoded Proteins
IDBP-129159
TBC1 domain family, member 10c
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175463:
The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4184358-4191047
Strand Reverse strand
Band A
Transcripts
ENSMUST00000045864 ENSMUSP00000042660
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0008150 biological_process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000175463
View Gene Order
ENSBTAG00000013133
Not yet available
Cross-References
SwissProt Q8C9V1
TrEMBL
UniProt Splice Variant
Entrez Gene 108995
UniGene
RefSeq NM_178650 XM_006531626 XM_006531627 XM_006544884 XM_006544885
OMIM
CCDS CCDS37885
HPRD
IMGT
MGI ID MGI:1922072
MGI Symbol Tbc1d10c
EMBL AK038366 AK040487 AK075803 AK088119 AK131177 AK146426
GenPept BAC30605 BAC35971 BAC40158 BAD21427 BAE20537 BAE27160
RNA Seq Atlas 108995

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca