Version 5.4
Mus musculus Gene: Ndufaf6
Summary
InnateDB Gene IDBG-129226.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufaf6
Gene Name NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
Synonyms 2310030N02Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000050323
Encoded Proteins
IDBP-129228
RIKEN cDNA 2310030N02 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156170:
This gene encodes a protein that localizes to mitochondria and contains a predicted phytoene synthase domain. The encoded protein plays an important role in the assembly of complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain through regulation of subunit ND1 biogenesis. Mutations in this gene are associated with complex I enzymatic deficiency. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:11051045-11076205
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000058183 ENSMUSP00000062039
ENSMUST00000144475
ENSMUST00000126468
ENSMUST00000124607
ENSMUST00000154122
ENSMUST00000148127
ENSMUST00000141019
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016740 transferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156170
View Gene Order
ENSBTAG00000007570
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275265
RefSeq NM_001085493 XM_006538358
OMIM
CCDS CCDS38691
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca