Mus musculus Gene: Zmynd11 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-129466.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Zmynd11 | ||||||||||||||||||||||
Gene Name | zinc finger, MYND domain containing 11 | ||||||||||||||||||||||
Synonyms | 2210402G22Rik; BS69 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000021156 | ||||||||||||||||||||||
Encoded Proteins |
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
zinc finger, MYND domain containing 11
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||||||||||||
Summary |
[Homo sapiens] Nuclear ZMYND11 is recruited by oligomerized, cytoplasmic TICAM1 to enhance NF-kappaB activation and type-I-interferon induction. ZMYND11 harbours dual modes of cytoplasmic NF-kappaB regulation, positively in the TICAM1 pathway and negatively in the PDLIM7 (LMP1) pathway.
[Homo sapiens] ZMYND11 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.
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Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000015171:
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 13:9684836-9765321 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | A1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | D3YY86 D3Z662 | ||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 66505 | ||||||||||||||||||||||
UniGene | Mm.397307 Mm.473000 Mm.473030 Mm.488717 | ||||||||||||||||||||||
RefSeq | NM_001199141 NM_144516 XM_006516503 XM_006516504 XM_006516505 XM_006516506 XM_006516507 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS36590 CCDS56870 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1913755 | ||||||||||||||||||||||
MGI Symbol | Zmynd11 | ||||||||||||||||||||||
EMBL | AC146596 AC153144 | ||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | 66505 | ||||||||||||||||||||||