Version 5.4
Mus musculus Gene: Calb1
Summary
InnateDB Gene IDBG-130445.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Calb1
Gene Name calbindin 1
Synonyms Brain-2; Calb; Calb-1; CB
Species Mus musculus
Ensembl Gene ENSMUSG00000028222
Encoded Proteins
IDBP-130447
calbindin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104327:
Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:15881264-15908064
Strand Forward strand
Band A2
Transcripts
ENSMUST00000029876 ENSMUSP00000029876
ENSMUST00000136266
ENSMUST00000141336
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005499 vitamin D binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007611 learning or memory
GO:0007614 short-term memory
GO:0007616 long-term memory
GO:0007626 locomotory behavior
GO:0010842 retina layer formation
GO:0035502 metanephric part of ureteric bud development
GO:0048167 regulation of synaptic plasticity
GO:0051480 cytosolic calcium ion homeostasis
GO:0060041 retina development in camera-type eye
GO:0071310 cellular response to organic substance
GO:0072205 metanephric collecting duct development
GO:0072221 metanephric distal convoluted tubule development
GO:0072286 metanephric connecting tubule development
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030424 axon
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0044297 cell body
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104327
View Gene Order
ENSBTAG00000015924
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.277665 Mm.396106
RefSeq NM_009788
OMIM
CCDS CCDS17984
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca