Version 5.4
Mus musculus Gene: Fam59a
Summary
InnateDB Gene IDBG-130655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam59a
Gene Name family with sequence similarity 59, member A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042680
Encoded Proteins
IDBP-130657
family with sequence similarity 59, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141441:
This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:21127201-21300138
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000049260 ENSMUSP00000048914
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070064 proline-rich region binding
Biological Process
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0051781 positive regulation of cell division
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071364 cellular response to epidermal growth factor stimulus
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141441
View Gene Order
ENSBTAG00000020286
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3UFT3
TrEMBL
UniProt Splice Variant
Entrez Gene 381126
UniGene Mm.461493
RefSeq NM_001033445
OMIM
CCDS CCDS29091
HPRD
IMGT
MGI ID MGI:2685790
MGI Symbol Garem
EMBL AC127570 AC158774 AK148318 AK162177 AK220564 BC049983 CH466557
GenPept AAH49983 BAD90542 BAE28477 BAE36773 EDK96964
RNA Seq Atlas 381126

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca