Version 5.4
Mus musculus Gene: Rbm28
Summary
InnateDB Gene IDBG-130805.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbm28
Gene Name RNA binding motif protein 28
Synonyms 2810480G15Rik; AI503051
Species Mus musculus
Ensembl Gene ENSMUSG00000029701
Encoded Proteins
IDBP-130807
RNA binding motif protein 28
IDBP-624655
RNA binding motif protein 28
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106344:
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:29123573-29165006
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000007993 ENSMUSP00000007993
ENSMUST00000169214
ENSMUST00000164563 ENSMUSP00000127856
ENSMUST00000170750
ENSMUST00000170473
ENSMUST00000172346
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
Cellular Component
GO:0005681 spliceosomal complex
GO:0005730 nucleolus
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106344
View Gene Order
ENSBTAG00000017001
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.40802
RefSeq NM_133925 XM_006505162 XM_006505163
OMIM
CCDS CCDS51733
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca