Version 5.4
Mus musculus Gene: Mapre2
Summary
InnateDB Gene IDBG-131276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mapre2
Gene Name microtubule-associated protein, RP/EB family, member 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024277
Encoded Proteins
IDBP-131278
microtubule-associated protein, RP/EB family, member 2
IDBP-248773
microtubule-associated protein, RP/EB family, member 2
IDBP-401721
microtubule-associated protein, RP/EB family, member 2
IDBP-532852
microtubule-associated protein, RP/EB family, member 2
IDBP-621561
microtubule-associated protein, RP/EB family, member 2
IDBP-621564
microtubule-associated protein, RP/EB family, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166974:
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:23752333-23893861
Strand Forward strand
Band A2
Transcripts
ENSMUST00000025127 ENSMUSP00000025127
ENSMUST00000115830 ENSMUSP00000111496
ENSMUST00000118826 ENSMUSP00000114113
ENSMUST00000132286
ENSMUST00000155708 ENSMUSP00000118807
ENSMUST00000149943
ENSMUST00000141853
ENSMUST00000165387 ENSMUSP00000131142
ENSMUST00000170802 ENSMUSP00000128040
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0007067 mitotic nuclear division
Cellular Component
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0035371 microtubule plus-end
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166974
View Gene Order
ENSBTAG00000007520
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.132237 Mm.472238 Mm.472593 Mm.488872
RefSeq NM_001162941 NM_001162942 NM_153058 XM_006525744 XM_006525745
OMIM
CCDS CCDS29095 CCDS50237 CCDS50238
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca